San Francisco 49ers vs Detroit Lions Predictions | Free NFL Picks Week 1 and Best Bets

San Francisco 49ers vs Detroit Lions picks and predictions. Bet your football predictions at BetUS. Sign-up at BetUS TODAY and get a 125% sportsbook bonus up to $2500 by using the NFL Promo Code NFL2021 at: https://bit.ly/BetUSNFL2021

BetUS host Matt Landes is joined by expert sports bettors Las Vegas Cris and Scott Kellen to preview the Week 1 matchup between the San Francisco 49ers and the Detroit Lions.

Topics:
NFL Week 1
San Francisco 49ers vs Detroit Lions Preview
San Francisco 49ers vs Detroit Lions Odds
San Francisco 49ers vs Detroit Lions Predictions

#NFLPicks #SFvsDET
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