The #49ers will be playing the #Patriots this upcoming Sunday Oct 25. That should be the hottest topic going towards game time, but the concern for who will be available for the Sunday matchup is the big issue. The #Niners will be taking on New England with plenty of backups. Some substitute ball players however do peak a curiosity in a positive fashion. We’ll be talking about the injuries and the intrigue of some of the players about to gain the opportunity to impress tonight.