NFL Week 1 Picks and Predictions - New Orleans Saints vs Tampa Bay Buccaneers (Sun, 9/13, 4:25 PM)

New Orleans Saints vs Tampa Bay Buccaneers NFL Week 1 picks, predictions, and odds for their showdown on Sunday, September 13. Direct from Las Vegas, the WagerTalk TV handicapping crew look at the Vegas odds and give their NFL expert picks and predictions on the matchup between the Saints and Buccaneers from Mercedes-Benz Superdome, New Orleans. Current NFL odds from Vegas have New Orleans favored by -3.5 over Tampa Bay with an over/under of 49.

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